Plant Transcription Factor Database
Previous version: v3.0
Lotus japonicus
WOX Family
Species TF ID Description
Lj1g3v1663420.1WOX family protein
Lj2g3v2702340.1WOX family protein
Lj4g3v3114830.1WOX family protein
Lj0g3v0258089.1WOX family protein
Lj2g3v0661590.1WOX family protein
Lj0g3v0172009.1WOX family protein
Lj0g3v0172009.2WOX family protein
Lj3g3v3188580.4WOX family protein
Lj2g3v1695340.1WOX family protein
Lj0g3v0135189.1WOX family protein
Lj0g3v0134389.1WOX family protein
Lj6g3v2006250.1WOX family protein
Lj0g3v0134389.2WOX family protein
Lj1g3v3992540.1WOX family protein
Lj4g3v1726060.1WOX family protein
Lj1g3v3218010.1WOX family protein
Lj1g3v3218010.2WOX family protein
Lj5g3v2264060.1WOX family protein
Lj5g3v2264060.2WOX family protein
Lj1g3v3384730.1WOX family protein
WOX Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401

The WOX genes form a plant-specific subclade of the eukaryotic homeobox transcription factor superfamily, which is characterized by the presence of a conserved DNA-binding homeodomain. The analysis of WOX gene expression and function shows that WOX family members fulfill specialized functions in key developmental processes in plants, such as embryonic patterning, stem-cell maintenance and organ formation. These functions can be related to either promotion of cell division activity and/or prevention of premature cell differentiation.

van der Graaff E, Laux T, Rensing SA.
The WUS homeobox-containing (WOX) protein family.
Genome Biol, 2009. 10(12): p. 248.
PMID: 20067590